Excuse my late entry: I live in Angola, not Mozambique. Malaria is the prime reason of child death under age of 5 (one in 5 dies). Locals and foreign residents obviously cannot run chemo throughout the year.
As a longterm resident with my family out here we choose to use mozi nets and use repelents. The garden is infested with the breed. Every other day I spray, just to keep them at level. Sector spraying also in the house to keep the plague out.
Still:
within 4 years, all my kids attracted malaria, the two middle boys in deep trouble (ICU) with non-indicating test at the childrens clinic... Raouli almost died in my arms, when his organs started to fail... 10 days intensive care in Luanda, too weak to evacuate, then his kidneys jumped back to work, Holy Lord. Our friends, my wife and me had to give blood and praying did the rest in junction with solid effort of our team of Angolan doctors.
Carefull:
I feel we are still not at the core of the challenge. Malaria kills. It kills your kids, kills your wife and finally get´s to you.
Prevent, rather than treat:
On a brief winter holiday, just the finest three weeks of July, leaving kids without chemo is plain madness. Us adults might have the reflex and keep using repelents, but not our "cassules" fresh out of the pool or beach. One sting is enough and the drama will engulf your family. We don´t want to have that stuff in our blood.
My very serious advice: Chemo plus nets plus repellents.
Travel safely, enjoy the tropics, have fun.